MY8100331A - Thiomethyl ergolene derivatives - Google Patents
Thiomethyl ergolene derivativesInfo
- Publication number
- MY8100331A MY8100331A MY331/81A MY8100331A MY8100331A MY 8100331 A MY8100331 A MY 8100331A MY 331/81 A MY331/81 A MY 331/81A MY 8100331 A MY8100331 A MY 8100331A MY 8100331 A MY8100331 A MY 8100331A
- Authority
- MY
- Malaysia
- Prior art keywords
- compound
- formula
- group
- proviso
- heteroatoms
- Prior art date
Links
- 125000000066 S-methyl group Chemical group [H]C([H])([H])S* 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 4
- 125000005842 heteroatom Chemical group 0.000 abstract 3
- 125000004105 2-pyridyl group Chemical group N1=C([*])C([H])=C([H])C([H])=C1[H] 0.000 abstract 2
- IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical compound N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 abstract 2
- 239000001257 hydrogen Substances 0.000 abstract 2
- 229910052739 hydrogen Inorganic materials 0.000 abstract 2
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 2
- 125000000339 4-pyridyl group Chemical group N1=C([H])C([H])=C([*])C([H])=C1[H] 0.000 abstract 1
- WKBOTKDWSSQWDR-UHFFFAOYSA-N Bromine atom Chemical compound [Br] WKBOTKDWSSQWDR-UHFFFAOYSA-N 0.000 abstract 1
- ZAMOUSCENKQFHK-UHFFFAOYSA-N Chlorine atom Chemical compound [Cl] ZAMOUSCENKQFHK-UHFFFAOYSA-N 0.000 abstract 1
- PXGOKWXKJXAPGV-UHFFFAOYSA-N Fluorine Chemical compound FF PXGOKWXKJXAPGV-UHFFFAOYSA-N 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 229910052783 alkali metal Chemical group 0.000 abstract 1
- 150000001340 alkali metals Chemical group 0.000 abstract 1
- 125000003545 alkoxy group Chemical group 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- GDTBXPJZTBHREO-UHFFFAOYSA-N bromine Substances BrBr GDTBXPJZTBHREO-UHFFFAOYSA-N 0.000 abstract 1
- 229910052794 bromium Inorganic materials 0.000 abstract 1
- 229910052799 carbon Inorganic materials 0.000 abstract 1
- 125000004432 carbon atom Chemical group C* 0.000 abstract 1
- 229910052801 chlorine Inorganic materials 0.000 abstract 1
- 239000000460 chlorine Substances 0.000 abstract 1
- 125000004093 cyano group Chemical group *C#N 0.000 abstract 1
- RHGUXDUPXYFCTE-ZWNOBZJWSA-N ergoline Chemical class C1=CC([C@@H]2[C@H](NCCC2)C2)=C3C2=CNC3=C1 RHGUXDUPXYFCTE-ZWNOBZJWSA-N 0.000 abstract 1
- 229910052731 fluorine Inorganic materials 0.000 abstract 1
- 239000011737 fluorine Substances 0.000 abstract 1
- QARBMVPHQWIHKH-UHFFFAOYSA-N methanesulfonyl chloride Chemical compound CS(Cl)(=O)=O QARBMVPHQWIHKH-UHFFFAOYSA-N 0.000 abstract 1
- 229910052757 nitrogen Inorganic materials 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- LMBFAGIMSUYTBN-MPZNNTNKSA-N teixobactin Chemical compound C([C@H](C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CO)C(=O)N[C@H](CCC(N)=O)C(=O)N[C@H]([C@@H](C)CC)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CO)C(=O)N[C@H]1C(N[C@@H](C)C(=O)N[C@@H](C[C@@H]2NC(=N)NC2)C(=O)N[C@H](C(=O)O[C@H]1C)[C@@H](C)CC)=O)NC)C1=CC=CC=C1 LMBFAGIMSUYTBN-MPZNNTNKSA-N 0.000 abstract 1
- 125000004149 thio group Chemical group *S* 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D457/00—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid
- C07D457/02—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid with hydrocarbon or substituted hydrocarbon radicals, attached in position 8
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CH356374A CH593972A5 (en]) | 1974-03-14 | 1974-03-14 | |
| CH1013874 | 1974-07-23 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MY8100331A true MY8100331A (en) | 1981-12-31 |
Family
ID=25693324
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MY331/81A MY8100331A (en) | 1974-03-14 | 1981-12-30 | Thiomethyl ergolene derivatives |
Country Status (18)
| Country | Link |
|---|---|
| JP (1) | JPS589111B2 (en]) |
| AU (1) | AU500890B2 (en]) |
| CA (1) | CA1071192A (en]) |
| DD (1) | DD118428A5 (en]) |
| DE (1) | DE2509471A1 (en]) |
| DK (1) | DK141701B (en]) |
| ES (1) | ES435538A1 (en]) |
| FI (1) | FI60865C (en]) |
| FR (1) | FR2263774B1 (en]) |
| GB (1) | GB1497681A (en]) |
| HK (1) | HK8481A (en]) |
| IE (1) | IE41533B1 (en]) |
| IL (1) | IL46809A (en]) |
| MY (1) | MY8100331A (en]) |
| NL (1) | NL7502807A (en]) |
| NO (1) | NO750748L (en]) |
| PH (1) | PH12966A (en]) |
| SE (1) | SE420094B (en]) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4147789A (en) * | 1974-03-14 | 1979-04-03 | Sandoz Ltd. | 6-Methyl-8-thiomethyl-ergolene derivatives |
| JPS5293797A (en) * | 1976-01-30 | 1977-08-06 | Sandoz Ag | Improvement in organic compound |
| GB1555751A (en) * | 1977-02-02 | 1979-11-14 | Farmaceutici Italia | Ergoline deritatives |
| US4166182A (en) * | 1978-02-08 | 1979-08-28 | Eli Lilly And Company | 6-n-propyl-8-methoxymethyl or methylmercaptomethylergolines and related compounds |
| US4382940A (en) * | 1979-12-06 | 1983-05-10 | Farmitalia Carlo Erba S.P.A. | Ercoline derivatives and therapeutic compositions having CNS affecting activity |
| GB2120242A (en) * | 1982-04-30 | 1983-11-30 | Erba Farmitalia | Ergoline derivatives |
| CH649998A5 (de) * | 1982-08-09 | 1985-06-28 | Sandoz Ag | Ergolinderivate, ein verfahren zu ihrer herstellung und heilmittel, enthaltend diese ergolinderivate als wirkstoff. |
| IT1215261B (it) * | 1985-04-05 | 1990-01-31 | Poli Ind Chimica Spa | Composizioni farmaceutiche adattivita' antigalattopoietica. |
| US4798834A (en) * | 1987-08-31 | 1989-01-17 | Eli Lilly And Company | Optionally substituted (3β-9,10-didehydro-2,3-dihydro ergoline as serotonergic function enhancement |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NL6818658A (en]) * | 1968-01-18 | 1969-07-22 |
-
1975
- 1975-02-12 IE IE542/75A patent/IE41533B1/en unknown
- 1975-03-05 SE SE7502469A patent/SE420094B/xx unknown
- 1975-03-05 DK DK89375AA patent/DK141701B/da not_active IP Right Cessation
- 1975-03-05 DE DE19752509471 patent/DE2509471A1/de not_active Ceased
- 1975-03-06 FI FI750644A patent/FI60865C/fi not_active IP Right Cessation
- 1975-03-06 NO NO75750748A patent/NO750748L/no unknown
- 1975-03-10 GB GB9807/75A patent/GB1497681A/en not_active Expired
- 1975-03-10 NL NL7502807A patent/NL7502807A/xx not_active Application Discontinuation
- 1975-03-11 FR FR7507472A patent/FR2263774B1/fr not_active Expired
- 1975-03-12 PH PH16903A patent/PH12966A/en unknown
- 1975-03-12 DD DD184721A patent/DD118428A5/xx unknown
- 1975-03-12 IL IL46809A patent/IL46809A/xx unknown
- 1975-03-12 ES ES435538A patent/ES435538A1/es not_active Expired
- 1975-03-13 JP JP50029600A patent/JPS589111B2/ja not_active Expired
- 1975-03-13 CA CA221,971A patent/CA1071192A/en not_active Expired
- 1975-03-13 AU AU79057/75A patent/AU500890B2/en not_active Ceased
-
1981
- 1981-03-12 HK HK84/81A patent/HK8481A/xx unknown
- 1981-12-30 MY MY331/81A patent/MY8100331A/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| FI60865C (fi) | 1982-04-13 |
| IL46809A0 (en) | 1975-07-28 |
| IL46809A (en) | 1978-04-30 |
| CA1071192A (en) | 1980-02-05 |
| NL7502807A (nl) | 1975-09-16 |
| FR2263774B1 (en]) | 1978-08-04 |
| JPS589111B2 (ja) | 1983-02-18 |
| AU7905775A (en) | 1976-09-16 |
| DK141701C (en]) | 1980-10-20 |
| JPS50123698A (en]) | 1975-09-29 |
| HK8481A (en) | 1981-03-20 |
| IE41533B1 (en) | 1980-01-30 |
| SE420094B (sv) | 1981-09-14 |
| SE7502469L (en]) | 1975-09-15 |
| FI750644A7 (en]) | 1975-09-15 |
| FR2263774A1 (en]) | 1975-10-10 |
| PH12966A (en) | 1979-10-19 |
| DE2509471A1 (de) | 1975-09-18 |
| DD118428A5 (en]) | 1976-03-05 |
| GB1497681A (en) | 1978-01-12 |
| IE41533L (en) | 1975-09-14 |
| NO750748L (en]) | 1975-09-16 |
| ES435538A1 (es) | 1977-03-16 |
| FI60865B (fi) | 1981-12-31 |
| DK141701B (da) | 1980-05-27 |
| DK89375A (en]) | 1975-09-15 |
| AU500890B2 (en) | 1979-06-07 |
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